CONTENTS
· Faculty
· Scientific Agenda
· Invitation
· Continuing
  Medical Education
· Who Should Attend?
· Objectives
· Registration
· General Information
· Hotel
  Accommodations
· Organizer

Susana Campos, MD
Dana-Farber Cancer Institute
Harvard Medical School
Boston, Massachusetts

Steven E. Come, MD
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Maura N. Dickler, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

Sharon H. Giordano, MD, MPH
MD Anderson Cancer Center
Houston, Texas

Timothy J. Hobday, MD
Mayo Clinic
Rochester, Minnesota

Kevin S. Hughes, MD, FACS
Massachusetts General Hospital
Boston, Massachusetts

Bernard T. Lee, MD
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Nancy Lin, MD
Dana-Farber Cancer Institute
Harvard Medical School
Boston, Massachusetts

Charles L. Loprinzi, MD
Mayo Clinic
Rochester, Minnesota

Eleftherios P. Mamounas, MD, MPH
Aultman Cancer Center
Canton, Ohio

Alvaro Moreno-Aspitia, MD
Mayo Clinic
Jacksonville, Florida

Hyman B. Muss, MD
University of Vermont
Burlington, Vermont

Frances Palmieri, RN, MSN, OCN
Mayo Clinic
Jacksonville, Florida

Ann H. Partridge, MD, MPH
Dana-Farber Cancer Institute
Harvard Medical School
Boston, Massachusetts

Edith A. Perez, MD
Mayo Clinic
Jacksonville, Florida

Abram Recht, MD
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Heidi Schulz, RN, OCN
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Dennis C. Sgroi, MD
Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Sumner Slavin, MD
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts

Victor G. Vogel, MD, MHS, FACP
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania

David E. Wazer, MD
Tufts-New England Medical Center
Boston, Massachusetts

Friday, October 6, 2006

Pre-conference Program: Challenges in Breast Cancer Nursing

8:30
Welcome
Abram Recht, MD and Edith A. Perez, MD

8:35
Radiotherapy after surgery
Abram Recht, MD

9:00
Questions

9:05
Nursing care of the patient receiving radiation therapy
Heidi Schulz, RN, OCN

9:20
Questions

9:35
Break

9:50
Hormone therapy for early disease
Edith A. Perez, MD

10:15
Questions

10:20
Toxicities associated with newer agents: What to look for and what to do
Frances Palmieri, RN, MSN, OCN

10:45
Questions

10:50
Critical assessment of quality of life: Outcomes measurement
Ann H. Partridge, MD, MPH

11:15
Questions

11:20
Lunch

General Sessions - Friday, October 6, 2006

Welcome and Introductory Lecture

12:00
Welcome and Introduction
Edith A. Perez, MD

Session I: Breast cancer: Prevention, detection, and prognosis

12:05
Gene expression testing: Dispelling the myths
Dennis C. Sgroi, MD

12:35
Optimization of chemoprevention strategies
Victor G. Vogel, MD, MHS, FACP

1:05
Panel discussion

Session II: Surgery

1:20
Prevention and control of lymphedema
Sumner Slavin, MD

1:50
New opportunities in breast reconstruction
Bernard T. Lee, MD

2:10
Break

Session III: Radiotherapy

2:40
Postmastectomy radiotherapy options
Abram Recht, MD

3:10
Partial breast irradiation: Which patients and under what circumstances?
David E. Wazer, MD

3:40
Management of patients with positive sentinel nodes
Kevin S. Hughes, MD, FACS

4:10
When to say no: Which patients with invasive cancer do not 'need' radiotherapy?
Abram Recht, MD

4:40
Questions

4:55
Adjourn

Saturday, October 7, 2006

8:30
Welcome to day two
Abram Recht, MD

Session IV: Early and locally advanced disease

8:35
Pros and cons of ovarian ablation
Susana Campos, MD

9:05
Taxanes as neoadjuvant therapy
Eleftherios P. Mamounas, MD, MPH

9:35
Update on aromatase inhibitors
Alvaro Moreno-Aspitia, MD

10:05
Break

10:25
Trastuzumab for early disease: How far we have come and where we are heading
Edith A. Perez, MD

10:55
Systemic treatment for elderly patients
Hyman B. Muss, MD

11:25
Which patients with ER+ disease should not receive adjuvant chemotherapy?
Steven E. Come, MD

11:55
Questions

12:10
Lunch

Session V: Disease management

1:15
Management of brain metastases in HER-2 overexpressing patients
Nancy U. Lin, MD

1:45
Therapy associated bone loss
Charles L. Loprinzi, MD

2:15
Panel discussion

2:45
Break

Session VI: Advanced/aggressive breast cancer

3:10
Taxanes in the adjuvant setting
Timothy J. Hobday, MD

3:40
Bevacizumab as front-line therapy
Maura N. Dickler, MD

4:10
Therapy options for inflammatory breast cancer
Sharon H. Giordano, MD, MPH

4:40
Panel discussion

4:55
Closing statements and adjourn

Dear Colleague,

It is with great pleasure and enthusiasm that we invite you to attend the 12th Perspectives in Breast Cancer. Over the past twelve years, this meeting has been become a dynamic forum for leaders in breast cancer research and patient care to increase their knowledge and share their challenges and successes in disease management and patient care.

It is common knowledge that breast cancer is the second leading cause of cancer mortality. Nearly 300,000 women in the United States will be diagnosed with some form of the disease. Significant media and medical attention to this disease has stimulated a large body of research dedicated to the detection, diagnosis, treatment and prevention of breast cancer, and as a result, our knowledge of the etiology and mechanisms of the disease has unfolded at a highly accelerated pace. The wealth of available data in this rapidly evolving field makes it difficult for practitioners to weed out quality research and pertinent data. Thus, this conference is designed to provide you, as a practicing clinician, with a comprehensive overview of this important and evolving field. Our panel, which is comprised of leading clinicians and researchers involved with breast cancer, will provide the latest information on state-of-the-art developments from the leading cancer centers and academic institutions.

Please join us in Boston for a rewarding professional update.

Sincerely,

Edith A. Perez, MD
Co-Chair

Abram Recht, MD
Co-Chair

PHYSICIANS: Imedex^®, Inc. is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Imedex, Inc. designates this educational activity for a maximum of 11.00 category 1 credits toward the AMA Physician’s Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

NURSES: This program (1006) has been approved by an AACN Certification Corporation-approved provider (Provider #00013328) under established AACN Certification Corporation guidelines for a maximum of 13.0 contact hours, CERP Category A.

This educational program is intended for physicians in active clinical practice, clinical researchers, nurses and healthcare administrators who are interested and/ or involved in the management of breast cancer. No specialized knowledge or skills other than a general familiarity with cancer and its treatment is required for successful participation in this program.

PHYSICIANS: After successful completion of this activity, participants should be able to:

• Understand the latest developments in surgery, radiation therapy, and systemic therapy for breast cancer
• Advise patients with ductal carcinoma in situ, early-stage or metastatic cancer on the most appropriate treatment(s)
• Adapt the management of breast cancer patients in light of the latest clinical research findings
• List the most promising future strategies for the management of breast cancer
• List the latest and most important prognostic and predictive factors in breast cancer
• Select the most appropriate techniques for screening, diagnosis, and initial evaluation of breast cancer

Click here to register for this program

REGISTRATION FEES

Discounted $195
If payment received by August 24, 2006

Regular $295
If payment received by September 28, 2006

Full On-Site $395
If payment received after September 28, 2006

Nurses/Residents/Students* $75
*proof of eligibility must accompany registration

Group Discount* - $50
*physicians only

To Register: You may register online or call Imedex at +1 (678) 242 0906. Registration confirmations will be issued before the meeting.

To qualify for special registration fees, registration and full payment must be received by Imedex by the dates specified.

Group Discounts
Multiple registrants from the same institute or practice each receive a $50 discount off the published registration fees, provided all registration forms and payments are received together. Only one discount will apply per physician. Discounts are not available for Nurses/Residents/Students rate.

Payment
Registration fees and hotel reservation guarantees can be remitted by credit card, check or wire transfer. Checks should be payable to Imedex. To pay via wire transfer, you must add $25 to the registration fee to cover bank charges. Include the full name of the attendee and the name of the conference: 264-Perspectives in Breast Cancer. Attendee is not registered until full payment is received.

Wire to: Bank of America, ABA: 0260.0959.3, Account Info: Imedex, Inc., Account: 0000.0106.3308. If the wire originates outside the United States, please add this additional information: Clearing Bank: Bank of America, New York, Swift Code: BOFAUS3N, Clearing Account: 6550305831.

Registration Fee Inclusions
Registration fees include admittance to scientific sessions, conference materials and all functions as specified in the program.

Cancellation
For registration fees to be refunded, written notice of cancellation must be received at Imedex by September 28, 2006. The amount of registration fees remitted, minus a $75 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. After September 28, 2006 no refunds will be made.

For hotel deposits to be refunded, written notice of cancellation must be received at Imedex no later than 5 business days prior to your scheduled arrival date. All refunds will be processed after the conference. Hotel rooms are not guaranteed after September 14, 2006.

Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this program should be cancelled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event program content is subject to change without notice.

Conference Location and Registration Hours:
The Westin Copley Place
10 Huntington Avenue
Boston, Massachusetts 02116
Tel.: +1 (617) 262-9600
Fax: +1 (617) 424-7483

The Registration and Information Desk will be staffed:
Friday, October 6, 2006 . . . . . . 7:30 am – 5:30 pm
Saturday, October 7, 2006 . . . . 7:30 am – 4:45 pm

The Westin Copley Place
10 Huntington Avenue
Boston, Massachusetts 02116
Tel.: +1 (617) 262-9600
Fax: +1 (617) 424-7483

The Westin Copley Place, Boston is an idyllic urban retreat for travelers, set in the center of one of historic Boston's finest neighborhoods, Back Bay. The hotel is located near Harvard University, MIT (Massachusetts Institute of Technology), the New England Aquarium, Fenway Park, Paul Revere's House, the USS Constitution (Old Iron Sides) and the Boston Common.

The hotel features amenities such as Westin's exclusive 10-layer Heavenly Bed®, an indoor pool, shopping in the retail gallery at Copley Place, and skywalk access to more than 100 shops at Copley Place, as well as the newly-opened Grettacole Spa.

For the convenience of attendees, a limited number of rooms has been reserved at a rate of $293, single or double occupancy, plus tax, currently at 12.45%. This rate is not guaranteed outside the conference dates. Hotel rooms may not be available after September 14, 2006.

For individual reservations, please submit a completed hotel reservation form. For group hotel reservations, groups should contact Imedex directly. Imedex will attempt to meet all accommodation requests, however, it reserves the right to change the requested hotel to one of a similar category if unable to confirm the hotel described in this brochure.

          4325 Alexander Drive
          Alpharetta, GA 30022-3740 USA
          Tel.: +1 (770) 751 7332
          Fax: +1 (770) 751 7334
          Email: meetings@imedex.com
          Web: http://www.imedex.com/