CONTENTS
· Welcome
· Faculty
· Scientific Agenda
· Who Should Attend?
· Continuing Medical Education
· Objectives
· Call for Abstracts
· Registration
· General Information
· Hotel Accommodations
· Organizer

Dear Colleagues,

It is with great pleasure that we invite you to join us for the 10th International Symposium on Febrile Neutropenia. This conference in Brussels, Belgium, 8-9 February 2008, promises to be our most valuable meeting yet!

The continued growth and success of this conference over the past few years has been a true testimony of the need for a meeting focusing on febrile neutropenia. Attendees have offered praise for the quality of the scientific agenda and the faculty, and have stated that participation in this conference significantly enhances their knowledge of the implications and management of
febrile neutropenia.

This conference is specifically designed for medical oncologists, infectious disease specialists, radiation oncologists, and other healthcare professionals interested and involved in the treatment of patients with febrile neutropenia. Our panel of international experts will touch on the most salient aspects of the etiology, diagnosis, and state-of-the art management of febrile neutropenia. Continuing with our successful abstract submissions tradition, we will again be accepting abstracts for both oral and poster presentations. We look forward to reviewing and sharing your research findings with the community.

We hope you will be able to join us for what is sure to be a rewarding and dynamic experience, as your perspectives and contributions add immeasurable value to this international symposium. We look forward to seeing you in Brussels!

Chair
Jean A. Klastersky, MD, PhD

Local Chair
Johan Maartens, MD

Co-Chairs
J. Peter Donnelly, PhD
Miguel A. Sanz, MD, PhD
John R. Wingard, MD

Matti S. Aapro, MD
Institut Multidisciplinaire d’Oncologie
Genolier, Switzerland

Elias J. Anaissie, MD
University of Arkansas for Medical Sciences
Little Rock, Arkansas
United States

Mickael Aoun, MD, PhD
Jules Bordet Institute
Brussels, Belgium

Rene-Jean Bensandoun, MD
Centre Antoine Lacassagne
Nice, France

Nicole M.A. Blijlevens, MD, PhD
University Medical Center St. Radbound
Nijmegen, The Netherlands

J. Peter Donnelly, PhD
University Medical Center St. Radbound
Nijmegen, The Netherlands

Marie-Thérèse Genot, MD, DDS
Jules Bordet Institute
Brussels, Belgium

Marcus Gorschluter, MD
University of Bonn
Bonn, Germany

Jean A. Klastersky, MD, PhD
Jules Bordet Institute
Brussels, Belgium

Johan Maertens, MD
University Hospital
Leuven, Belgium

Francesco Menichetti, MD
Cisanello Hospital
Pisa, Italy

Kenneth V. Rolston, MD
M. D. Anderson Cancer Center
Houston, Texas
United States

Miguel A. Sanz, MD, PhD
University Hospital La Fe
Valencia, Spain

John R. Wingard, MD
University of Florida Shands Cancer Center
Gainesville, Florida
United States

Friday, 8 February 2008

8:00 Introduction
Jean A. Klastersky, MD, PhD

Session I: Fungal infections
Chair: Johan Maertens, MD

8:10
Emerging fungal pathogens
Elias J. Anaissie, MD

8:55
Discussion

9:10
Oral abstracts

9:20
Oral abstracts

9:30
Oral abstracts

9:40
Break

10:00
Case presentation: Relapsing fever in transplanted patients with pulmonary and cerebral
lesions
Mickael Aoun, MD, PhD

10:45
Case presentation: Zygomycetes: An emerging problem
Johan Maertens, MD

11:30
Session Chair’s summary
Johan Maertens, MD

12:00
Lunch

Session II: Typhlitis
Chair: J. Peter Donnelly, PhD

13:30
Neutropenic enterocolitis: An extreme form of mucosal barrier injury
Nicole M.A. Blijlevens, MD, PhD

14:15
Discussion

14:30
Oral abstracts

14:40
Oral abstracts

14:50
Oral abstracts

15:00
Break

15:20
Case presentation: Chemotherapy induced enterocolitis
Kenneth V. Rolston, MD

16:05
Case presentation: Candida enterocolitis
Marcus Gorschluter, MD

16:50
Session chair’s summary
J. Peter Donnelly, PhD

17:20
Adjourn

Saturday, 9 February 2008

Session III: G-CFS’s
Chair: John R. Wingard, MD

8:10
Overview of the role for myeloid colony stimulating factors and antibiotics in the prevention of neutropenic fever
John R. Wingard, MD

8:35
Discussion

8:50
Myeloid colony stimulating factors have an important role in preventing neutropenic fever
Matti S. Aapro, MD

9:25
Discussion

9:40
Break

10:00
Antibiotics have an important role in preventing neutropenic fever
Francesco Menichetti, MD

10:30
Discussion

10:45
Oral abstracts

10:55
Oral abstracts

11:05
Oral abstracts

11:15
Discussion

11:30
Session chair’s summary
John R. Wingard, MD

Session IV: Mucositis
Chair: Jean A. Klastersky, MD, PhD

13:30
New insights into the pathogenesis and recent progresses in the management of oral mucositis in cancer patients
Marie-Thérèse Genot, MD, DDS

14:15
Discussion

14:30
Oral abstracts

14:40
Oral abstracts

14:50
Oral abstracts

15:00
Break

15:20
Case presentation: The heavily treated hematological malignancy patient
Nicole M.A. Blijlevens, MD, PhD

16:05
Case presentation: The patient with radiation therapy associated mucositis
Rene-Jean Bensandoun, MD

16:50
Session chair’s summary
Jean A. Klastersky, MD, PhD

17:20
Adjourn with summary by chair and local chair
Jean A. Klastersky, MD, PhD and Johan Maertens, MD

This conference is specifically designed for medical oncologists, infectious disease specialists, radiation oncologists, and other healthcare professionals interested and
involved in the treatment of patients with
febrile neutropenia. Our panel of international experts will touch on the most salient aspects
of the etiology, diagnosis, and state-of-the art management of febrile neutropenia.

Accreditation
10th International Symposium on Febrile Neutropenia is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net.

10th International Symposium on Febrile Neutropenia is designated for a maximum of 12 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

EACCME credits are recognized by the American Medical Association towards the Physician's Recognition Award (PRA). To convert EACCME credit to AMA PRA category 1 credit, contact the AMA.

After successful completion of this continuing medical education activity, participants should be able to:

• Identify emerging treatment strategies for fungal infections in febrile neutropenic patients
  
• Summarize and outline recent data surrounding the management strategies for enterocolitis in febrile neutropenic patients
  
• Discuss and evaluate the role of granulocyte colony stimulating factors in the prevention of febrile neutropenia
  
• Describe the pathogenesis, implications, and recent advances in the management of mucositis in febrile neutropenic patients
  
• Compare current and emerging therapies in the prevention and management of febrile neutropenic patients
  

Click here to register online.

Regular . . . . . . . . . . . . . . . . . . . . €625
If payment received by 29 January 2008

Full/Onsite . . . . . . . . . . . . . . . . . . €695
To register after 29 January 2008

Nurses/Residents/Students* . . . . . . €200
*Proof of eligibility must accompany registration

To Register: You may register online by 29 January 2008 or by calling Imedex at +1 (678) 242 0906. Registration confirmations will be issued before the conference. To qualify for special registration fees, registration and full payment must be received by Imedex by the dates specified.

Payment: To pre-register, registration and payment must be received no later than 29 January 2008. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure the program is being held as scheduled and to confirm that the meeting is not full. Registration fees must be remitted by credit card, check, or wire transfer. Checks should be payable to Imedex. To pay via wire transfer, you must add €50 to each wire transaction to cover bank charges. Include the full name of the attendee and the name of the conference: 10th International Symposium on Febrile Neutropenia # 309. An attendee is not registered until full payment is received.

Wire to: Bank of America, NA London, 1 Alie Street E1ADE London UK, Swift Code: BOFAGB22, Sort Code: 165050 Beneficiary: Bank of America Domestic Deposit #5687, Account #: 600895687029, Reference: Imedex, Inc. Account # 10726-118, IBAN: GB89 BOFA 1650 5095 6870 29.

Registration Fee Inclusions: Registration fees include admittance to all scientific sessions, conference materials, processing of certificates of attendance or continuing medical education, and all event functions as specified in the agenda.

Cancellation: For registration fees to be refunded, written notice of cancellation must be received by Imedex at meetings@imedex.com no later than 29 January 2008. The amount of registration fees remitted, minus a €90 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after 29 January 2008.

Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this program should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda content is subject to change without notice.

Conference Location and Registration Hours
Hotel Metropole S.A.
31, Place de Brouckere
B-1000 Brussels
Tel.: + 32 2 2172300
Fax: + 32 2 2142510
www.metropolhotel.com

The Registration and Information Desk
will be staffed:
Friday, 8 February 2008....................07:00 – 17:20
Saturday, 9 February 2008...............07:30 – 17:20

Italian Participants
Fargo International Meetings & Conventions SRL has been appointed as the official agency for government authorization for Italian participants.

You may contact them directly at:
Fargo International Meetings & Conventions SRL
Via Piattro Maroncelli 44/66, 50137 Firenze, Italy
Tel.: +39 055 600 555
Fax: +39 055 609 078

Hotel Metropole S.A.
31, Place de Brouckere
B-1000 Brussels
Tel.: + 32 2 2172300
Fax: + 32 2 2142510
www.metropolehotel.com

The Metropole Hotel is marvelously well located right in the historical center of the European capital, just a few steps away from the 'Grand-Place', the 'Bourse' and the 'Théâtre de la Monnaie' and close
to the city's most exciting shopping thoroughfare of Brussels.

Built in 1895, and the only remaining hotel of the 19th century, the Metropole Hotel offers all
the comfort of a Great Luxury Hotel and is noticeable by the quality of its service and its internal decoration.

For the convenience of attendees, a limited number of rooms have been reserved until 14 January 2008 at a discounted rate of € 150 single/double occupancy, plus VAT, currently at 21%. This rate is not guaranteed outside the Conference dates or after 14 January 2008.

To reserve your room please contact the Hotel Metropole reservations department at
+ 32 2 2172300. To receive the group rate, callers must identify themselves as being with the 10th International Symposium on Febrile Neutropenia group.

          4325 Alexander Drive
          Alpharetta, GA 30022-3740 USA
          Tel.: +1 (770) 751 7332
          Fax: +1 (770) 751 7334
          Email: meetings@imedex.com
          Web: www.imedex.com