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Focus on Fungal Infections 19

March 4 - 6, 2009

Sanibel Island, Florida

Sanibel Harbour

In affiliation with the Medical Mycological Society of the Americas

Continuing Medical Education

accme Imedex, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Imedex, LLC designates this educational activity for a maximum 14.5 of AMA PRA Category 1 Credit ^TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Imedex has applied for approval as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program.

Who Should Attend

This educational activity is specifically designed for infectious disease specialists, microbiologists, epidemiologists, laboratory technologists, and other healthcare professionals with special education and training in microbiology or infectious diseases who are interested in the identification, diagnosis, and management of invasive fungal infections.

Objectives

After successful completion of this activity, attendees should be able to:

Discuss and implement the optimal utilization of antifungal agents to treat patients with invasive candidiasis
Review and debate the appropriate usage of the antifungal regimen when treating patients with invasive aspergillosis
Compare and contrast the clinical management of invasive mycotic infections based upon regional epidemiological studies
Discuss the methods which healthcare professionals can provide effective clinical management of zygomycosis based upon the current studies
Summarize and discuss the characteristics of the newer antifungal agents and their respective clinical trials

Elias J. Anaissie, MD
University of Arkansas for Medical Sciences
Little Rock, Arkansas

Jeremy Ryan Bariola, MD
University of Arkansas for Medical Sciences
Little Rock, Arkansas

John E. Bennett, MD
National Institutes of Health
Bethesda, Maryland

Eric J. Bow, MD
CancerCare Manitoba Health Sciences Centre
Winnipeg, Manitoba

Arnaldo L. Colombo, MD, PhD
Federal University of São Paulo
São Paulo, Brazil

J. Peter Donnelly, PhD
Radboud University Nijmegen Medical Center
Nijmegen, Netherlands

Annette W. Fothergill, MA, MBA
The University of Texas Health Science Center at San Antonio
San Antonio, Texas

Mahmoud A. Ghannoum, PhD
University Hospitals of Cleveland and Case Western Reserve University
Cleveland, Ohio

Paul O. Gubbins, PharmD
University of Arkansas for Medical Sciences
Little Rock, Arkansas

Tobias M. Hohl, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

David Horn, MD
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania

Michael Kleinberg, MD, PhD
University of Maryland Greenebaum Cancer Center
Baltimore, Maryland

Kieren A. Marr, MD
Fred Hutchinson Cancer Research Center
Seattle, Washington

Marcio Nucci, MD
Federal University of Rio de Janeiro
Rio de Janeiro, Brazil

Ali Olyaei, PharmD
Oregon Health and Science University
Portland, Oregon

Luis Ostrosky-Zeichner, MD, FACP
The University of Texas Health Science Center at Houston
Houston, Texas

Peter G. Pappas, MD
University of Alabama at Birmingham
Birmingham, Alabama

Benjamin J. Park, MD
Centers for Disease Control and Prevention
Atlanta, Georgia

Thomas F. Patterson, MD, FACP, FIDSA
University of Texas Health Science Center at San Antonio
San Antonio, Texas

John R. Perfect, MD
Duke University Medical Center
Durham, North Carolina

Michael A. Pfaller, MD
University of Iowa College of Medicine
Iowa City, Iowa

Gary W. Procop, MD
Cleveland Clinic
Cleveland, Ohio

Annette C. Reboli, MD
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School
Camden, New Jersey

Michael G. Rinaldi, PhD
University of Texas Health Science Center at San Antonio
San Antonio, Texas

Glenn D. Roberts, MD
Mayo Clinic
Rochester, Minnesota

Coleman Rotstein, MD, FRCPC, FACP
Toronto General Hospital
Toronto, Ontario, Canada

Brahm H. Segal, MD
Roswell Park Cancer Institute
Buffalo, New York

David A. Stevens, MD
Santa Clara Valley Medical Center
San Jose, California

Deanna A. Sutton, PhD
University of Texas Health Science Center at San Antonio
San Antonio, Texas

Theklis Zaoutis, MD, MSCE
The Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Thomas J. Walsh, MD
National Cancer Institute
Bethesda, Maryland

Wednesday, March 4, 2009

2:00 pm Mycology Workshop
Annette W. Fothergill, MA, MBA and
Deanna A. Sutton, PhD

4:00 pm Break

4:15 pm MMSA — Mycology Workshop 101
Glenn D. Roberts, MD and Gary W. Procop, MD

5:30 pm Adjourn

Thursday, March 5, 2009

7:45 am Welcome/Audience Response System demographic questions
Elias J. Anaissie, MD and Michael G. Rinaldi, PhD

Session I: Epidemiological trends in invasive fungal infections
Moderator: Michael G. Rinaldi, PhD

8:00 am From the CDC: Update on the TRANSNET database and recent epidemiological investigations
Benjamin J. Park, MD

8:20 am Epidemiological trends in invasive fungal infections from a cohort of more than 6900 patients at 24 North American centers (2004-2008)
David Horn, MD

Session II: Candidiasis
This session brought to you in collaboration with INFOCUS Latin America and the International Pediatric Fungal Network
Moderator: TBD

8:40 am Audience Response System Case #1
A patient with hematogenous candidiasis after liver transplantation

8:50 am Geographic variability in the epidemiology of Candidiasis
Arnaldo L. Colombo, MD,PhD

9:10 am Risk factors in non-neutropenic hosts
Luis Ostrosky-Zeichner, MD, FACP

9:30 am Diagnosis: Conventional tools and other new developments
Michael A. Pfaller, MD

9:50 am Panel discussion of Audience Response System Case #1 with audience participation

10:10 am Coffee Break

10:30 am Audience Response System Case #2
Septic shock caused by Candida albicans in a patient with cancer

10:40 am Risk factors in neutropenic patients
Coleman Rotstein, MD, FRCPC, FACP

11:00 am Notable trends in antifungal susceptibility of Candida species
Mahmoud A. Ghannoum, PhD

11:20 am Antifungal agents for prophylaxis, preemption or for proven candidiasis?
Annette C. Reboli, MD

11:40 am An analysis of antifungal dosing patterns from a cohort of more than 6900 patients at 24 North American centers (2004-2008)
Ali Olyaei, PharmD

12:00 pm What is new in neonatal candidiasis?
Theoklis Zaoutis, MD, MSCE

12:20 pm Panel discussion of Audience Response System Case #2 with audience participation

12:35 pm Lunch

Session III: Candidiasis (2)
This session brought to you in collaboration with INFOCUS Latin America

Moderator: Coleman Rotstein, MD, FRCPC, FACP

2:00 pm Managing venous catehrters: Remove them all
Peter G. Pappas, MD

2:20 pm Managing venous catherters: Maybe, but first show me the data
Marcio Nucci, MD

2:40 pm Questions

2:50 pm Break

Session IV: Zygomycosis
This session brought to you in collaboration with the International Immunocompromised Host Society
Moderator: John R. Perfect, MD

3:10 pm Audience Response System Case #3
A patient with rhinocerebral infection and diabetic ketoacidosis

3:20 pm Zygomycosis or not: Diagnostic pitfalls and promises
Thomas J. Walsh, MD

3:40 pm The management of zygomycosis in patients with metabolic/immunologic dysregulations
Thomas F. Patterson, MD, FACP, FIDSA

4:00 pm Antifungal therapy: Polyenes, posaconazole or prayers?
Michael Kleinberg, MD, PhD

4:20 pm Panel discussion of Audience Response System case #3 with audience participation

4:40 pm Poster viewing

5:00 pm Adjourn

Friday, March 6, 2009

7:30 am Poster Viewing Session

8:00 am Welcome
Elias J. Anaissie, MD and Michael G. Rinaldi, PhD

Session V: Aspergillosis
Moderator: Thomas F. Patterson, MD, FACP, FIDSA

8:05 am Audience Response System Case #4
A liver transplant recipient develops aspergillosis

8:15 am Epidemiology: "The times, they are a-changin"
Kieren A. Marr, MD

8:35 am Risk factors: Immunity is everything (almost)
David A.Stevens, MD

8:55 am Aspergillosis in neutropenic patients
Eric J. Bow, MD

9:15 am Panel discussion of Audience Response System cases with audience participation

9:35 am Coffee Break

9:55 am Debate: Antifungal agents for prophylaxis, preemption, or for proven aspergillosis
Point: Prophylaxis
Brahm H. Segal, MD
Counterpoint: Diagnosis-based preemptive therapy
J. Peter Donnelly, PhD

10:35 am Selection of the optimal antifungal for all the right reasons: Susceptibility/resistance, adverse events, drug interactions and tissue penetration
John E. Bennett, MD

10:55 am Therapeutic drug monitoring: The do's and don'ts
Paul O. Gubbins, PharmD

11:15 am Treatment of endemic mycoses: Updates on the IDSA guidelines
Jeremy Ryan Bariola, MD

11:35 am Panel discussion of Audience Response System case #4 with audience participation

11:55 am Lunch

Session VI: The future of fungal infections
Moderator: David A. Stevens, MD

2:00 pm The functional genomics of host defense
Thomas J. Walsh, MD

2:20 pm Cracking the fungal armor
Tobias M. Hohl, MD

2:40 pm New targets for antifungal agents and updates on recent clinical trials
TBD

3:00 pm Presentation of Awards
Elias J. Anaissie, MD and Michael G. Rinaldi, PhD

4:15 pm Adjourn

Registration Fees

Discounted
Physician $299
Pharmacist $175
If payment received by March 1, 2009

Full/Onsite
Physician $499
Pharmacist $250
If payment received after March 1, 2009

Group discount (physicians only)* -$50
*Cannot be combined with any other discounts

Nurses/Residents/Students $99

To Register: You may register online by March 1, 2009 or by calling Imedex at +1 (678) 242 0906. Registration confirmations will be issued before the meeting.

To qualify for special registration fees, registration and full payment must be received by Imedex by the dates specified.

The Registration and Information Desk at the Sanibel Harbour will be staffed:
Wednesday, March 4, 2009
12:30 pm - 4:00 pm

Thursday, March 5, 2009
7:00 am – 4:30 pm

Friday, March 6, 2009
7:00 am – 4:00 pm

Group Discounts: Each one of multiple registrants from the same institute or practice receives a $50 discount off the published registration fees, provided all registration forms and payments are received together. Only one discount will apply per physician. Discounts are not available for pharmacist rate.

Payment: To pre-register, registration and payment must be received no later than March 1, 2009. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure the course is being held as scheduled and to confirm that the meeting is not full. Registration fees must be remitted by credit card or check. Checks should be payable to Imedex. Attendee is not registered until full payment is received.

Registration Fee Inclusions: Registration fees include admittance to all scientific sessions, conference materials, processing of certificates of attendance or continuing medical education, and all event functions as specified in the program.

Cancellation: For registration fees to be refunded, written notice of cancellation must be received at meetings@imedex.com no later than March 1, 2009. The amount of registration fees remitted, minus a $75 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after March 1, 2009.

Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this program should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda is subject to change without notice.

Hotel Accommodations

Sanibel Harbour
17260 Harbour Point Dr
Fort Myers, Florida 33908
Tel.: +1 (239) 466 4000
Fax: +1 (239) 466 2150
www.sanibel-resort.com

Sanibel Harbour is a 85-acre bayside hotel situated on a private peninsula on Florida’s southwest coast overlooking Sanibel and Captiva islands. Guest rooms, meeting space and other common areas, combined with newly concepted restaurants and lounges have captured the ambiance of a stately Florida plantation home.

Dining options include the Courtside Steakhouse with a casual sports club ambiance and 1,200-bottle wine cellar. Charley’s Cabana Bar offers an island happy-hour spirit with views and a selection of flatbreads and tapas. Recalling the ambiance of an old seaside plantation library, The Banyan Room brings guests the flavors of the Mediterranean. A family-friendly seafood restaurant, the Tarpon House offers relaxing, waterfront views.

For the convenience of attendees, a limited number of rooms have been reserved until February 10, 2009 at a discounted rate of $299.00 single/double occupancy, plus tax, currently at 11% and a $15.00 per day resort fee. This rate is not guaranteed outside the conference dates or after February 10, 2009.

To reserve your room, please contact the Sanibel Harbour Resort & Spa reservations department at +1 (239) 466-4000 or +1 (800) 767-7777. To receive the group rate, callers must identify themselves as being with the Imedex group.

Discounted Airfares
Contact Congress travel agent, Williamsburg Travel, for assistance with your travel needs. Williamsburg Travel can also accommodate pre- and post-Congress extensions.
Tel.: +1 (888) 232 9394 or +1 (770) 261 8613
Email: judit@willtrav.com

19 Years of Exceptional Educational Value

With a spotlight on both clinical and laboratory aspects of antifungal therapy and a variety of educational tools to instruct its diverse audience, Focus on Fungal Infections has become a leading international forum for world leaders in mycology and infectious disease management to share and increase their knowledge of fungal infections and how to optimize patient care. The educational content of the meeting, speaker quality, presentation quality and organizational quality are consistently highly rated, providing attendees with a superior educational event.

Distinguished Faculty of Key Opinion Leaders

Focus on Fungal Infections provides attendees with a premium opportunity to interact with the distinguished faculty that includes expert academicians, private practice physicians, laboratory specialists and specialized veterinarians. Two and 1/2 days of study in a targeted forum provide a valuable opportunity to focus your attention on the topic at hand.

ORGANIZER

Imedex
4325 Alexander Drive
Alpharetta, GA 30022-3740 USA
Tel.: +1 (770) 751 7332
Fax: +1 (770) 751 7334
Email: meetings@imedex.com
Web: www.imedex.com

Significant Impact on Clinical Practice

More than 400 physicians, laboratory technologists, pharmacists and other healthcare professionals attend Focus on Fungal Infections annually. Past participants value the scope and depth of the information presented, and many return year after year for the newest updates.

Medical Mycology 101

This is an introductory workshop from MMSA that is designed to provide basic understanding of diagnostic medical mycology. The course is intended for residents, fellows, technologists, or other professionals who seek a foundation in medical mycology. The course complements the preceding highly successful and well established “Mycology Workshop.”

Abstract Awards

The Scientific Committee annually recognizes the efforts of researchers who make significant contributions in medical mycology through esteemed and highly competitive awards for both established and young investigators. We invite you to submit your studies for consideration.

Imedex is a brand and assumed name used by Imedex, LLC (hereby referred to as Imedex). Imedex is solely responsible for this agenda's content. Although Imedex attempts to ensure that the information in our program is accurate and timely, matters and opinions discussed and/or presented with respect to clinical matters are those of the discussion participants only, and not necessarily those of Imedex. Moreover, although Imedex attempts to identify and integrate the most qualified medical professionals in our program, TO THE FULLEST EXTENT PERMITTED BY LAW, IMEDEX EXPRESSLY DISCLAIM ALL WARRANTIES, EITHER EXPRESS OR IMPLIED, STATUTORY OR OTHERWISE, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OF MERCHANTABILITY, NON-INFRINGEMENT OF THIRD PARTIES' RIGHTS, AND FITNESS FOR A PARTICULAR PURPOSE, WITH RESPECT TO THE CONTENT PRESENTED. IMEDEX FURTHER MAKES NO REPRESENTATIONS OR WARRANTIES ABOUT THE ACCURACY, RELIABILITY, COMPLETENESS OR TIMELINESS OF THE CONTENT OR ANY MATERIAL PRESENTED.

In addition, the material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual's own physician.

Neither Imedex nor any of its subsidiaries or affiliates is affiliated with or formally endorsed by a medical society.

The following companies have provided an unrestricted educational grant in support of this Conference:

PLATINUM

GOLD

Pfizer

CORPORATE

enzon

EXHIBITOR

mechanisms in motion

miravista

REALTIME LABORATORIES, LLC

Several options are available to companies interested in supporting this Congress. For more information, please contact Imedex at +1(770) 751 7332, or by email at cme@imedex.com.