The American School of Oncology™

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Target Audience
This educational activity is specifically designed for hematologists, oncologists, internists and other physicians, physicians-in-training, and healthcare professionals (nurses and pharmacists) involved in and/or interested in lymphoma, myeloma, and related plasma cell disorders and their management.

Overview
The annual Lymphoma & Myeloma meeting took place in New York City on October 18-20, 2007. Internationally known researchers and practitioners presented new and emerging therapeutic methods useful in treating the lymphomas, multiple myeloma, and plasma cell disorders. The Lymphoma & Myeloma 2007 conference was developed with the endeavor of producing an educational format that combines didactic sessions and panel discussions led by leaders in the field. This Webcast is taken directly from that meeting.

Educational Objectives
After completing this activity, the participant will be able to:

  • Review updates in the biology of myeloma, lymphoma, and related plasma cell disorders
  • Utilize new diagnostic and prognostic indicators in myeloma, lymphoma, and related plasma cell disorders
  • Identify the most important genetic and molecular abnormalities of myeloma and lymphoma cells
  • Implement the latest first-line therapies in myeloma and lymphoma, and related plasma cell disorders
  • Improve management of relapsed/refractory disease in myeloma and lymphoma
  • Employ state-of-the-art therapies for both early and advanced lymphomas
  • Implement evidence-based management strategies for the various types and stages of lymphoma, myeloma, and related plasma cell disorders
  • Recognize available new drugs, as well as emerging therapies in the pipeline, for the treatment of myeloma, lymphoma, and related plasma cell disorders

Disclosure Statement
As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), Imedex®, LLC must ensure balance, objectivity, independence, and scientific rigor in its educational activities. Faculty are encouraged to provide a balanced view of therapeutic options by utilizing generic names of several to ensure impartiality.

All faculty participating in an Imedex activity are required to disclose commitments to and/or relationships with pharmaceutical companies, biomedical device manufacturers or distributors, or others whose products or services may be considered to be related to the subject matter of the educational activity. Disclosure of these commitments and/or relationships is included in these course materials so that participants in the activity may formulate their own judgments in interpreting its content and evaluating its recommendations.

The following indicates the faculty disclosure declaration information and the nature of those commercial relationships.

1=grant/research support 2=consultant 3=speaker’s bureau 4=stock shareholder 5=other support

Myron S. Czuczman, MD BEN Program3
James Dahlberg, PhD National Institute of Health1; Third Wave Technologies, Inc.2,4
Robert O. Dillman, MD, FACP AstraZeneca Pharmaceuticals LP4, Bristol-Myers Squibb Company1,4, Johnson & Johnson4, NovaRx Corporation2, Pfizer Inc4, Schering-Plough Corporation4
Rafael Fonseca, MD Pfizer Inc1
Francine Foss, MD MERCK & CO., Inc.3; Therakos, Inc.2
Richard R. Furman, MD BioCryst Pharmaceuticals, Inc.2
Neil E. Kay, MD Hospira, Inc.1
Emilio Montserrat, MD Amgen Inc.1, Roche Laboratories Inc.1,2, Münch Pharma2
Paul G. Richardson, MD Johnson & Johnson3
G. David Roodman, MD, PhD Amgen Inc.2; MERCK & CO., Inc.2; Multiple Myeloma Research Foundation1; National Institute of Health/ Institute of Arthritis and Musculoskeletal and Skin Diseases 1; VA Merit Review1
John D. Shaughnessy Jr, PhD ZymoGenetics1,5
Sonali M. Smith, MD Astellas Pharma Inc.2
Donna Weber, MD MERCK & CO., Inc.1
Anas Younes, MD Methylgene Inc.1, Seattle Genetics1

The following speakers have reported an affiliation with the supporters of this conference:

Kenneth C. Anderson, MD, MA Celgene Corporation1,2,3; Millennium Pharmaceuticals, Inc.1,2,3; Novartis Pharmaceuticals Corporation1,2,3
Bart Barlogie, MD, PhD Celgene Corporation1,3 ; Millennium Pharmaceuticals, Inc.1,3
Asher A. Chanan-Khan, MD Celgene Corporation1,2,3; Millennium Pharmaceuticals, Inc.1,3
Bruce D. Cheson, MD Biogen Idec Inc.3; Celgene Corporation2, Genentech BioOncology3
Myron S. Czuczman, MD Biogen Idec Inc.1,5, Genentech BioOncology1
Robert O. Dillman, MD, FACP Abbott Laboratories4, Bayer HealthCare Corporation5, Biogen Idec Inc.1,3,4, Genentech BioOncology3,4, GlaxoSmithKline4, Onyx Pharmaceuticals Inc.5
Angela Dispenzieri, MD Celgene Corporation1
Richard I. Fisher, MD Genentech BioOncology2,3,5 ; GlaxoSmithKline2,3,5 ; Millennium Pharmaceuticals, Inc.2,3,5
Rafael Fonseca, MD Celgene Corporation2; Millennium Pharmaceuticals, Inc.2
Francine Foss, MD Genentech BioOncology3, Gloucester Pharmaceuticals, Inc.2
Neil E. Kay, MD Bayer HealthCare Corporation1, Celgene Corporation2
David G. Maloney, MD, PhD Biogen Idec Inc.2, Genentech BioOncology1,2, GlaxoSmithKline2, Gcam M 762
Graham Mead, MD The Binding Site Ltd.5
Ruben Niesvizky, MD Celgene Corporation3; Millennium Pharmaceuticals, Inc.3; Novartis Pharmaceuticals Corporation3; OrthoBiotech Products, L.P.3
Carol S. Portlock, MD Genentech BioOncology3, Biogen Idec Inc.3
Kanti Rai, MD BerlexLaboratories, Inc./Bayer HealthCare Corporation1
S. Vincent Rajkumar, MD Celgene Corporation1
Paul G. Richardson, MD Celgene Corporation3; Millenium Pharmaceuticals, Inc.3
G. David Roodman, MD, PhD Celgene Corporation3; Millennium Pharmaceuticals, Inc.2,3; Novartis Pharmaceuticals Corporation2,3
John D. Shaughnessy Jr, PhD Celgene Corporation1,2; Millennium Pharmaceuticals, Inc.1,5; Novartis Pharmaceuticals, Inc.1,5
Sonali M. Smith, MD Biogen Idec Inc.2,3, Genentech BioOncology2,3
David Vesole, MD, PhD, FACP Celgene Corporation3; Millennium Pharmaceuticals, Inc.3,4; Ortho Biotech Products, L.P.1,2,3
Donna Weber, MD Celgene Corporation1,3; Millennium Pharmaceuticals, Inc.2,3
Anas Younes, MD Genentech BioOncology1

The following speakers do not report any affiliation:

Raymond Alexanian, MD
Maurizio Bendandi, MD, PhD
Amy Chadburn, MD
Selina Chen-Kiang, PhD
Nicholas Chiorazzi, MD
Morton Coleman, MD
Raymond L. Comenzo, MD
Volker Diehl, MD
Scott Ely, MD
Randy D. Gascoyne, MD
Philip R. Greipp, MD
Sandra J. Horning, MD
Lale Kostakoglu, MD
Robert A. Kyle, MD
John P. Leonard, MD
Ari Melnick, MD
Saul A. Rosenberg, MD
Jia Ruan, MD, PhD
David J. Straus, MD
Wyndham H. Wilson, MD, PhD
Andrew D. Zelenetz, MD
Emanuele Zucca, MD

All materials are included with the permission of the authors.

All Imedex staff members who are in a position to control the content of this activity have no financial relationships with any commercial interests that are relevant to this activity.

Faculty

Raymond Alexanian, MD
M. D. Anderson Cancer Center
Houston, Texas

Kenneth C. Anderson, MD, MA
Dana-Farber Cancer Institute
Boston, Massachusetts

Bart Barlogie, MD, PhD
University of Arkansas Medical Center
Little Rock, Arkansas

Maurizio Bendandi, MD, PhD
University Clinic, Department of Hematology
Pamplona, Spain

Amy Chadburn, MD
Weill Medical College Of Cornell University
New York, New York

Asher A. Chanan-Khan, MD
Roswell Park Cancer Institute
Buffalo, New York

Selina Chen-Kiang, PhD
Weill Medical College Of Cornell University
New York, New York

Bruce D. Cheson, MD
Georgetown University Hospital
Washington, DC

Nicholas Chiorazzi, MD
North Shore - Long Island Jewish Research Institute
Manhasset, New York

Morton Coleman, MD
Center for Lymphoma and Myeloma
Weill Medical College of Cornell University
New York Presbyterian Hospitals
New York, New York

Raymond L. Comenzo, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

Myron S. Czuczman, MD
Roswell Park Cancer Institute
Buffalo, New York

James Dahlberg, PhD
The University of Wisconsin Madison
Madison, Wisconsin

Volker Diehl, MD
University of Cologne
Cologne, Germany

Robert O. Dillman, MD, FACP
Hoag Cancer Center
Newport Beach, California

Angela Dispenzieri, MD
Mayo Clinic College of Medicine
Rochester, Minnesota

Scott Ely, MD
Weill Medical College of Cornell University
New York Presbyterian Hospitals
New York, New York

Richard I. Fisher, MD
University of Rochester Medical Center
Rochester, New York

Rafael Fonseca, MD
Mayo Clinic
Scottsdale, Arizona

Francine Foss, MD
Yale Medical Oncology
New Haven, Connecticut

Richard R. Furman, MD
Center for Lymphoma and Myeloma
Weill Medical College of Cornell University
New York Presbyterian Hospitals
New York, New York

Randy D. Gascoyne, MD
British Columbia Cancer Center
Vancouver, British Columbia, Canada

Philip R. Greipp, MD
Mayo Clinic College of Medicine
Rochester, Minnesota

Sandra J. Horning, MD
Stanford University Medical Center
Stanford, California

Neil E. Kay, MD
Mayo Clinic
Rochester, Minnesota

Lale Kostakoglu, MD
Mount Sinai Medical Center
New York, New York

Robert A. Kyle, MD
Mayo Clinic
Rochester, Minnesota

John P. Leonard, MD
Center for Lymphoma and Myeloma
Weill Medical College of Cornell University
New York Presbyterian Hospitals
New York, New York

David G. Maloney, MD, PhD
Fred Hutchinson Cancer Research Center
Seattle, Washington

Graham Mead, MD
The Binding Site Ltd.
Birmingham, United Kingdom

Ari Melnick, MD
Albert Einstein College of Medicine
Bronx, New York

Emilio Montserrat, MD
University of Barcelona
Barcelona, Spain

Ruben Niesvizky, MD
Center for Lymphoma and Myeloma
Weill Medical College of Cornell University
New York Presbyterian Hospitals
New York, New York

Carol S. Portlock, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

Kanti Rai, MD
Long Island Jewish Medical Center
New Hyde Park, New York

S. Vincent Rajkumar, MD
Mayo Medical School
Rochester, Minnesota

Paul G. Richardson, MD
Dana-Farber Cancer Institute
Harvard Medical School
Boston, Massachusetts

G. David Roodman, MD, PhD
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania

Saul A. Rosenberg, MD
Stanford Comprehensive Cancer Center
Stanford, California

Jia Ruan, MD, PhD
Weill Medical College of Cornell University
New York Presbyterian Hospital
New York, New York

John D. Shaughnessy Jr, PhD
University of Arkansas for Medical Sciences
Little Rock, Arkansas

Sonali M. Smith, MD
University of Chicago
Division of Biological Sciences
Chicago, Illinois

David J. Straus, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

David Vesole, MD, PhD, FACP
St. Vincent's Comprehensive Cancer Center
New York, New York

Donna Weber, MD
M. D. Anderson Cancer Center
Houston, Texas

Wyndham H. Wilson, MD, PhD
National Cancer Institute
Bethesda, Maryland

Anas Younes, MD
M. D. Anderson Cancer Center
Houston, Texas

Andrew D. Zelenetz, MD
Memorial Sloan-Kettering Cancer Center
New York, New York

Emanuele Zucca, MD
Oncology Institute of Southern Switzerland
Bellinzona, Switzerland

Sponsorship Statement
This activity is sponsored by Imedex, LLC.

Accreditation Statement
Imedex, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Imedex, LLC designates this educational activity for a maximum of 18.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

In order to receive credit, participants must successfully complete the post-test and complete the online evaluation form. You will receive an online CME statement of credit to print for your records.

For questions regarding the accreditation of this activity, please contact

Imedex
4325 Alexander Drive
Alpharetta, GA 30022
Fax: +1(770) 751-7334
Email: enduring@imedex.com

Unapproved and Investigational Uses of Drug and Devices
This Webcast may contain information about experimental and other uses of drugs or devices that are not currently approved by the US Food and Drug Administration (FDA) and/or other national regulatory agencies in the United States and other countries. Participants in the United States are encouraged to consult the FDA-approved product labeling for any drug or device mentioned in this program before use. Participants from other countries should consult with their respective regulatory authorities.

The opinions expressed in this email case discussion are the opinions of the authors and do not necessarily reflect the opinions of Imedex, LLC.

Support
The following companies have provided unrestricted educational grants in support of this activity: Abbott Laboratories; Allos Therapeutics, Inc.; Bayer HealthCare Corporation; Onyx Pharmaceuticals Inc.; Biogen Idec Inc.; Celgene Corporation; Cephalon, Inc.; Favrille, Inc.; Genentech BioOncology; Genzyme Corporation; GlaxoSmithKline; Gloucester Pharmaceuticals; Johnson & Johnson; Eli Lily and Company; MedImmune Inc.; Millennium Pharmaceuticals Inc.; Novartis Pharmaceuticals Corporation; Ortho Biotech Products, L.P.; Proteolix, Inc.; Sigma -Tau; and The Binding Site Ltd.

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The American School of Oncology™